MMP-9 AND MG CHANGES IN CORD BLOOD IN TWO DIFFERENT MODES OF DELIVERY

الملخص

Objective: to investigate the changes in both serum MMP-9 and Mg levels and their effect on two different modes of delivery, normal vaginal (NVD) and elective cesarean section (C/S). Method: a case-control study design has been conducted between January 2015 and May 2016. The current study recruited 64 pregnant women at term gestation (37–41 completed weeks). They were approached from different hospitals in Baghdad. Umbilical cord blood serum magnesium was determined by colorimetric spectrophotometry using colorimetric enzymatic Kit and MMP-9 using Enzyme Liked immune-sorbent assay (ELISA) technique. Results: a highly significant increase in MMP-9 concentration was found in umbilical cord blood (UCB) of women sera delivered by C/S vis. women delivered normally NVD, while trace element concentration (Mg) was significantly lower in UCB sera of women sera delivered by C/S vis. women delivered normally NVD with p values < (0.001 and 0.021 respectively). Conclusion: the decrease of UCB serum magnesium level may effect on UCB serum MMP-9 level especially in women underwent CS.